Nuclear imaging for cardiac amyloidosis

Nuclear Imaging of Amyloidosis

Summary Amyloidosis is a clinical condition caused by deposition of various protein fibrills in extracellular space. The presented symptoms depend on the type of deposits and the organ or organs involved. The correct diagnosis is often difficult, due to lack of nonivasive imaging techniques and insufficiency of morphological imaging procedures delievered by radiology. We presented a list of pot...

Imaging cardiac innervation in amyloidosis.

Cardiac amyloidosis is a form of restrictive cardiomyopathy resulting in heart failure and potential risk on arrhythmia, due to amyloid infiltration of the nerve conduction system and the myocardial tissue. The prognosis in this progressive disease is poor, probably due the development of cardiac arrhythmias. Early detection of cardiac sympathetic innervation disturbances has become of major cl...

Nuclear tracers for transthyretin cardiac amyloidosis: time to bone up?

Magnetic resonance imaging in cardiac amyloidosis.

The amyloidoses are a group of uncommon systemic diseases characterized by the extracellular deposition of pathologic insoluble amyloid protein in organs and tissues. The are 4 main types of amyloidosis: primary (AL, the most prevalent type), familial, secondary, and senile. Each of them has its own physiopathology, distinctive features, and variable cardiac involvement. The symptoms of cardiac...

Typical cardiac magnetic resonance imaging findings of cardiac amyloidosis.

We report the case of a 62-year-old man who presented with shortness of breath, lower extremity edema and clinical signs of congestive heart failure. Transthoracic echocardiography demonstrated concentric left ventricular hypertrophy with severe diastolic dysfunction and biatrial enlargement. After aggressive diuresis and clinical improvement, a cardiac magnetic resonance imaging (CMR) examinat...